St Johns Wort Extract
St John’s Wort has also a long tradition of dermatological applications. Topically, it can be used to heal minor wounds and burns, sunburns, abrasions, bruises, contusions, ulcers, myalgia, and many others. A rub can also be used for aching muscles, relief of cramp and nerve pain.
Of the constituents, naphthodianthrones (e.g., hypericin) and phloro-glucinols (e.g.,hyperforin) have interesting pharmacological profiles, including antioxidant, anti-inflammatory, anticancer, and antimicrobial activities.
In addition, hyperforin stimulates growth and differentiation of keratinocytes, and hypericin is a photosensitizer which can be used for selective treatment of non melanoma skin cancer.
These activities suggest a potential benefit of using this old medicinal plant in skin diseases like atopic dermatitis, psoriasis, herpes infections, white skin cancer and general skin care. Water soluble extracts have also shown antimicrobial activity in
particularly to Staphylococcus aureus.